orb+chakram and discordance = awesome. The cooldown is a problem but once you have 45% reduced CD, you can work from there.
Also using Gauntlet with orb is powerful too along with hero points if you used discordance.
Even without discordance, orb from gauntlet deals more damage than the Zeus slicer in terms of base damage and if you used chakram on rogue or warrior hammer for orbs.
But Zeus is a good weapon to start off with for a reactor build like Duct Tape.