It works but a better method is farm floors above 100+ and when you farm so much angelites and quartz, you can salvage them down to calcite and they are just as easy as calcite. The white coloured crystals are common rank and very easy to find therefore very abundant. Even easier with proper farming gear. That is if you want to often use 1 character and not want to use other characters for farming but up to you
A key farming affix for crystals is item drops. The higher the item drops, the more crystals you will obtain ( as well as more legends,orbs,gold and mythstones).