1) Purpose of the guide:
This is not a single build or optimization guide. It is a general guide to help you choose what to use depending on your desires. It will start out very broad but then go into an abyss of details down to single affixes that affect your playstyle. As such I will not tell you what is best, I will do recommendation for synchronization purposes.
This is a very complex game. A single affix can and will change how you play. I will not go through all 370+ affixes. But the ones that affect playstyle will be covered in some shape or form.
The best thing about this game is that you do not need to get max affixes or fully optimized builds to do well. Just concentrate on having fun while achieving your goals. If you are looking at DPS optimization, I will cover basic formulas and some minor Affix comparisons. Nothing further than that.