Blood mage, full mana(299 points), and poison damages. You can use all the affixes for
+(element) damage %
+ poison related skills(can't think of names off the top of my head)
+Whatever other skills you choose to use
Note that while using this set you will only be able to use poison damage, however you will still show upwards of 1m-1.2m dps on paper, while being able to do significantly more with storm.
Alternatively, use ascendant with the same build, using an arcane weapon, obviously being able to hold your own against anything. With this build I have reached as high as 45k health, but was unable to surpass 750k dps with that. My other build yields 37k health and ~1.2m dps.