For people who do floor 0 to 200, having enough HP and MP with some regen and on hits, MP absorb with Alchemy is so good! Despite the alchemy making you take 50% of the HP/MP%, that MP absorb heals so much MP and eventually HP. Guidedshot with this or other great primary for the win for newbies and for high floor if you dodge.
MP and HP are treated like HP for taking hits. If you run out f HP, your MP gets taken before you finally die or Vice Versa. . MP and HP on hit heal your MP or HP and each other very well too.
For skill cost, it takes HP if you run out of MP to cast and vice versa. MP on Hit and HP on hit can influence how the mythic priorities resource and cost of resource. Regen too does this.
Fairy heal of course goes great. Heals MP or HP.
Masochism or Hunger do have weird Effects with Alchemy but when they work, they really do help a lot for DMG and utilise the potential of the mythic itself.
I definitely recommend this mythic to try out for primary skill build of the future.
Not good with manashield for obvious reasons.
It's not best for PvP although that could eventually change given the right circumstances. It did have a bug that made it a bit more powerful than it needed a year ago though.
If the MP and HP on hit heal consistently and are on similar levels, then more taking hits although casting skill costs some resource but MP absorb could help as well as some regen somewhere.
The cost of 50% more DMG based on how much MP/HP% you have will still be there though but if it's managed, you could do well. I could see that happening eventually.
Full resource means this won't happen until you get hit but if you take less dmg and manage the resource well, it could be a deadly force.