Can we get defiant by rerolling it?

Defiant cannot be obtained via Amethyst.

Does a Defiant works if youâ€™re HP turns to 1 by using 100% Glasscannon?

yes and no.

Defiant has a constant +25% Damage & Damage Reduction. this isnâ€™t affected by your HP.

itâ€™s +5% per Rank of your * current missing HP* that is affected by +100% Glasscannon. with only 1 HP, you will always be at 100% Health. which means if you go below 100% Health, you are dead and canâ€™t do any damage at all.

Defiant against monsters with Thorns is nice, since Thorns lowers your HP, your damage & damage reduction go up.

if you have Sanctuary and it gets activated, you are at -90% HP for a few seconds, which means about +45% damage & damage reduction, until you heal.

with Defiant (5), if your HP is cut in half to 50%, you get +37.5% Damage & Damage Reduction. this is why Defiant & Masochism work well together, as Masochism keeps your Health around 50%. Masochism wouldnâ€™t work with +100% Glasscannon either, as it will not reduce your HP below 1, so no damage from Masochism either, which requires your HP to be 75% or lower.

But the 1 HP by Glasscannon wonâ€™t work with Masochism, Iâ€™ve try that to equip but it doesnâ€™t damage my HP itself like my HP is constant

But which one is better Mr. Golem, 100 percent of Glasscannon or purely Masochism?

The best thing to do is intentionally have glass cannon NOT maxed at 100%, like try 99%

Iâ€™ll try it later but I donâ€™t know if what sets do I remove

lets look at the math.

Defiant & 2x Glasscannon is 1.25 x 2 = 2.5x damage.

Defiant, 1 Glasscannon, 1 Barbarian or Push the Limit is 1.25 x 1.5 x 1.5 = 2.812.

with these 2 combinations, you donâ€™t have to worry about your HP changing affecting your damage.

Defiant, Masochism, & 1 Glasscannon is 1.375 x 1.375 x 1.5 = 2.835. the damage will go up and down as your HP goes up and down, but Masochism works to keep your HP around 50%.

Defiant, Masochism, & 2 Glasscannon +75% is 1.375 x 1.375 x 1.75 = 3.308x damage.

Defiant, Masochism, 1 Glasscannon, 1 Barbarian or 1 Push the Limit is 1.375 x 1.375 x 1.5 x 1.5 = 4.253x damage.

with these 3 combinations, your damage will go up & down as your HP goes up and down, with Masochism working hard to keep your HP around 50%.

**Edit:** Barbarian & Push the Limit canâ€™t be rolled with Ruby. only found on Loot.