Seems ok but here’s some suggestions and what is your main damage. Is it skull or some special skill.
Change Mainhand to Gauntlet masochist for more DMG with 200% WD. How? Convert warrior axe masochism weapon with 200% WD by Jasper to wizard. That simple change should give a massive boost since sword on wizard has very low default base DMG and same with wand.
Other than that, not a bad build. You don’t really need 500% poison DMG though. 300% is more than enough imo to save slots for some other thing. Although it’s up to you as it’s totally powerful using 500% poison ED and 200% WD on gauntlet.
Not much else I can say really but lemme analyse it more. I think the build is well built. Maybe sanctuary for survival of you keep dying and spending too much gold, otherwise you should be fine with Empyrean.
Discordance is an interesting choice though. However it’s actually nerfing your storm DMG since you don’t have 4+ Extra Attack and 4+ Multi Attack.
So your storm deals 125% (150% with gauntlet) MH instead of 600%. Though with Discordance, you can get 150%×3 (4+ multi attack) ×1.484375 (4+ extra attack)×1.5 (push the limit) × 3 (storm hero points 40) = 3,005.859375% MH. Thats only if you add 4+ extra attack and 4+ Multi Attack . ATM your storm is very low MH%.
Although without Discordance your storm can be even better and for less cost. How? Storm 600%. Hero points 40 gets you at 1800% MH. Push the limit 50% gets you to 2700%. Well actually the discordance option does deal slightly more MH% but it costs more slots.
Replace Discordance with Energy/Fury. Maybe even alchemy if you know what you’re doing, though alchemy requires a balance of HP and MP and a good amount. Not the most slot friendly and better for primary skills Alchemy is. It’s either Energy or Fury.
Replace the 200% ED with 2× 2+ Multi attack and replace 5000 WD with 4+ Extra Attack mythstone if you’re using discordance.
Do try Demonic set over Pathfinder as one idea though. Momentum + adventurer.
Arcanist + ascendant does work but one way that could work is hirling ascendant but main character using Arcanist . Although your configuration would definitely work fine too. Seems like an ultimate build.
One thing you’re bottlenecked by is the discordance. Remove that, put energy and done. Discordance requires extra investment to make the most of it. Only really good for some skills and other classes.