Here's my current farm build. I'm working towards a similar build for floor climbing but I still need 2 epiphany items so here's what I'm using right now. I have about a 3 minute clear time on floor 601-605 which I'm repeatedly farming until I get my epiphany drops. With a bit of work I can clear enemy heal maps.
The Epiphany Necklace and Scorpio offhand will carry over to my final build but everything else will be replaced.