first take a look at the rest of your build, even the Stat Page.
keep the Nadroji Set until you can replace it with another Set Affix, unless you want to replace it with another Epic affix instead. you can always find another Nadroji Ring later if you need a Nadroji Set again.
the +3 All Skill only affects Weapon Skills, and that is a +15% DMG and 3 Skill Levels of other Bonus’s from the Weapon Skills you are using your Talents to see if you should keep it or replace it.
+2 All Sets. Winner! Winner! Winner! this is why everyone wants a Nadroji Ring and/or Necklace.
the Shock DMG, or ED%, you can keep this for extra DMG. just make sure the item is the same Element as your Weapons (use Calcite if necessary). if you need another affix, then change it.
the Total MP% is least useful, unless you really need extra MP to cast your Skills.
don’t forget, when using Angelite, as long as there is 5 affixes on an item, the sixth one will always be a random Epic affix. if there are four or less, including Sockets, then the next one is a chance to be Normal or Epic affix, until you have 5 affixes again, in which case, the sixth one will be Epic. so only take one affix off at a time so that you can get Epic affix. only use Kyanite to remove affixes, Quartz removes a random number of affixes, so you could end up losing that +2 All Sets and end up having to find another Nadroji.