As you progress through higher floors, enemy damage scales drastically to the point that monster can just 1 shot you no matter what, resists & damage reductions are pretty much irrelevant, instead, try investing on Dodge or Block, the higher the % the better. Also, skills with mobility will help you reposition yourself better to avoid enemy attacks.
I have several wizard builds that I can share to help you climb higher floors (I’m at Floor 3000+ M3), what kind of build are you looking for?
looking at the build, quad is using a Farm Build to climb floors.
in addition to all the things already mentioned, the builds damage potential is really low.
I would suggest using the build as is on a lower floor and working on a second build that has a focus on damage and defense for climbing floors.
another thing is getting Items with Crystal affixes or getting Obsidian crystals through farming, converting Items, or upgrading Crystals.
Epic +15% Attack Speed
Crystal +45% Attack Speed
floor level is part of the formula for damage reduction from Armor & All Resist, which causes Armor & All Resist to become weaker on higher floors.
use Diamond to get better affix values on all Legend Items with Legend (Red) affixes, then use Fluorite for each Epic (Orange) affix. don’t worry about affixes on the Pet, they will improve over time automatically.
read Codex > Dictionary > Affixes so that you know what affixes are available and what they do so that you can have an idea for future changes. with a Pet, there are only 42 spaces total for affixes, so it can get frustrating. I’ve been playing for years, and I still get frustrated with only 42 affixes per build.